Table 1: long term efficacy of antimicrobial activity, as measured in 10 % fetal bovine serum (fbs.)
Sample | Staph. aureus (cfu/ml) |
E. coli. (cfu/ml) |
18 hour contorl | 3.8 x 106 | 1.2 x 106 |
18 hour QMT sample | < 3 (6 log kill) | < 3 (6 log kill) |
3 day control | 4.3 x 106 | 6.0 x 106 |
3 day QMT sample | < 3 (6 log kill) | < 3 (6 log kill) |
7 day control | 6.5 x 106 | 3.7 x 106 |
7 day QMT sample | < 3 (6 log kill) | 4.4 x 102 ∼4 log kill |
Table 2: Bacteriocidal Efficacy Testing
Organism | % wound infection | % killed | ATCC# |
The most common wound-associated bacteria | |||
Staphylococcus aureus | 20% | >99.9999% | 12600, 6538 |
Staphylococcus epidermidis | 14% | >99.9999% | 12228 |
Enterococci spp | 12% | >99.9999% | 19433 |
Escherichia coli | 8% | >99.9999% | 15597, 8739 |
Pseudomonas aeruginosa | 8% | >99.9999% | 51447, 15442, 9027 |
Enterobacter spp | 7% | >99.9999% | 13048 |
Proteus spp | 3% | >99.9999% | 13115 |
Klebsiella pneumoniae | 3% | >99.9999% | 13833 |
Streptococci | 3% | >99.9999% | 10096 |
Additional common bacterial species associated with [body] odor | |||
Corynebacterium xerosis | >99.9999% | 7711 | |
Corynebacterium diptheriae | >99.9999% | 43145 | |
Micrococcus luteus | >99.9999% | 21102 | |
Proteus vulgaris | >99.9999% | 13115 | |
Additional common bacterial species associated with food contamination | |||
Listeria monocytogenes | >99.9999% | 13932 | |
Salmonella choleraesuis | >99.9999% | 10708 | |
Additional common bacterial species associated with burn wounds | |||
Serratia marcescens | >99.9999% | 13880 |
Table 3: Percentage of bacteria killed within the time indicated.
Time | Log Reduction of species, with ATCC numbers | ||||
SA(6538) | EC(15597) | PA(15442) | MRSA(BAA-44) | VRE(700221) | |
1 min | 3.76 | 4.43 | 3.64 | 3.87 | 2.29 |
10 min | 4.21 | 4.29 | 4.29 | 4.22 | 3.32 |
1 hr | 4.83 | 5.23 | 5.31 | 5.89* | 3.28 |
4 hrs | 6.23* | 5.72 | 6.40* | 5.89* | 5.63 |
- Denotes full kill; each measurement has an individual control thus inducing some variability in the numbers based on natural differences in the growth rates.
- Testing as per ASTM D-2315, using 10 % FBS as transfer medium.