Data Tables

Table 1: long term efficacy of antimicrobial activity, as measured in 10 % fetal bovine serum (fbs.)

Sample Staph. aureus
(cfu/ml)
E. coli.
(cfu/ml)
18 hour contorl 3.8 x 106 1.2 x 106
18 hour QMT sample < 3 (6 log kill) < 3 (6 log kill)
3 day control 4.3 x 106 6.0 x 106
3 day QMT sample < 3 (6 log kill) < 3 (6 log kill)
7 day control 6.5 x 106 3.7 x 106
7 day QMT sample < 3 (6 log kill) 4.4 x 102 ∼4 log kill

 

 

Table 2: Bacteriocidal Efficacy Testing

Organism % wound infection % killed ATCC#
The most common wound-associated bacteria
Staphylococcus aureus 20% >99.9999% 12600, 6538
Staphylococcus epidermidis 14% >99.9999% 12228
Enterococci spp 12% >99.9999% 19433
Escherichia coli 8% >99.9999% 15597, 8739
Pseudomonas aeruginosa 8% >99.9999% 51447, 15442, 9027
Enterobacter spp 7% >99.9999% 13048
Proteus spp 3% >99.9999% 13115
Klebsiella pneumoniae 3% >99.9999% 13833
Streptococci 3% >99.9999% 10096
Additional common bacterial species associated with [body] odor
Corynebacterium xerosis >99.9999% 7711
Corynebacterium diptheriae >99.9999% 43145
Micrococcus luteus >99.9999% 21102
Proteus vulgaris >99.9999% 13115
Additional common bacterial species associated with food contamination
Listeria monocytogenes >99.9999% 13932
Salmonella choleraesuis >99.9999% 10708
Additional common bacterial species associated with burn wounds
Serratia marcescens >99.9999% 13880

 

 

Table 3: Percentage of bacteria killed within the time indicated.

Time Log Reduction of species, with ATCC numbers
  SA(6538) EC(15597) PA(15442) MRSA(BAA-44) VRE(700221)
1 min 3.76 4.43 3.64 3.87 2.29
10 min 4.21 4.29 4.29 4.22 3.32
1 hr 4.83 5.23 5.31 5.89* 3.28
4 hrs 6.23* 5.72 6.40* 5.89* 5.63
  • Denotes full kill; each measurement has an individual control thus inducing some variability in the numbers based on natural differences in the growth rates.
  • Testing as per ASTM D-2315, using 10 % FBS as transfer medium.